Pointers required for mysterious Sending Mail message in Ooutlook

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I have recently noticed that Outlook is sending e-mails (usually 2)
when there is nothing in my Outbox - no sent mail is recorded in Sent
Items and it usually happens after startup/restart

Is this spyware/trojan horse/other malicious or unuauthorised

I do have McAfee installed including firewall...

Any hep appreciated,

Best regards,

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